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Home News Theory vascular blood pipeline: Logic and vector effects on vascular pathology in angiosurgery and angiotherapy.
Theory vascular blood pipeline: Logic and vector effects on vascular pathology in angiosurgery and angiotherapy. Print E-mail
MD Lushchyk UB professor., D f.-m. BC. Novitsky, V.
Center for Innovative Medical Technologies (Kyiv, Ukraine) U.Lushchyk @
     A growing negative statistics on progression strokes look younger and death from cardiovascular disease among the population of Ukraine and the world is at odds with the ability of modern diagnostic techniques for objectification vascular pathology.
    Cardiovascular system (CAS) of the body can be compared to the pipeline: a closed system of communicating tubes of different caliber, which thanks to the work of the heart as a pump provides blood flow in arteries and veins.
Therefore, we proposed a mathematical model of vascular pipeline, which reflects the movement of blood in a closed system with numerous blood vessels of various calibers, pressure, wall characteristics, elastic-tonic properties of the vascular wall, the distal resistance and others. and control of these parameters in the arterial, capillary and venous.
   Appointment vascular pipeline - uninterrupted blood supply to all organs and tissues of the human body. Capillaries - is the smallest blood vessels in the vascular pipeline, which reflect the state of the entire cardiovascular system at the level of microcirculation in the heart of the remotest parts of the human body. Therefore, as manifestations of cardiovascular and vascular organ vascular insufficiency, primarily suffers blood in the capillaries.
   Capillaries are the arbiters of well-being in the functioning of all segments of the CAS if the picture microcirculation in the normal range - this indicates a coordinated functioning of the heart, arteries and veins in the body. If not - then you need to pursue deeper afterexamination SSA to identify all pathological links in the CAS.
In the study of CAS should, however, bear in mind that blood - it non-Newtonian liquid which takes place according to certain laws.
   Science that studies the movement of blood in the vessels, called hemodynamics. It is part of the Fluid - basic science that studies the movement of fluids.
Unfortunately, it so happened that today none of the specialists who treat diseases of the cardiovascular system does not use the laws of hemodynamics. None of the doctors involved in the treatment of vascular disease and are unaware insights into the vascular system from this angle, and apply the laws of hemodynamics. So today in the treatment of cardiovascular diseases therapeutic strategy and tactics in anhiohirurhiyi and anhioterapiyi not always adequate and effective in assessing the final result.
   Vascular conduit is a very complex system. Unlike classical plumbing, vascular tube is flexible, cardiac pump pumps the blood in the vascular bed unevenly, vascular wall may be severally and pass fluid into the surrounding tissue. Therefore, the classical water feature can be regarded as stable when properly exhibited constant parameters diameter, water pressure, power discharge pump. Cardiovascular system belongs to a highly complex model for the regulation of vascular krovoprovodu because all hemodynamic parameters in it are constantly changing and adequate work should only be subject to the principles of autoregulation and synergies between different segments of CAS, changes intravascular longitudinal and transverse pressure and others., Balance inflow -outflow, arterio-venous and arteriolar-venulyarnoyi equilibrium.
    To a living organism to function in vascular pipeline has maintained a balance between:
• blood pressure and intravascular resistance
• arterial links in the main and peripheral segments of the vascular system,
• arteriolar and venular links on the microcirculatory level
• between wireframe and elastic resistance of the vascular wall and others.
   Thus, a kind of vascular homeostasis, so CCC can provide optimal conditions for the existence and functioning of the body.
If stability is violated at least one parameter of the vascular pipeline (eg reduction of vascular tone in vascular dystonia), then eventually even such seemingly minor crash leads to frustration of the entire vascular system in general and the progression of this pathological manifestations (including violation of propagation pulse wave and pressure of blood in the CCC), which causes the development of a disease - endarteritis, atherosclerosis, thrombosis, embolism, etc.).
   Disbalance functioning CCC reminds jarring December orchestra and complies with all the laws of development and growth of damaging for life processes - chaos - locally in one vascular pool (brain, kidney, liver, and so forth.) Or simultaneously in all. In such a case may collapse, thrombosis, sudden cardiac arrest, and (even) may occur clinical death.
   We distinguish three degrees of severity of chaos in the vascular system (first, second and third) - Chaos 1, 2 chaos, chaos 3.
Chaos in the vascular system by severity has three stages. Without appropriate (adequate) treatment of the third, the hardest stage sooner or later lead to decompensation in the CAS, since the unstable system can not function properly even in the background, but with the additional load suddenly suffers a serious malfunction.
Stroke, heart attack - a catastrophic conditions arising as a result of a pronounced imbalance of vascular function pipeline - decompensation CAS against the background of chaos expressed by 3 degrees.
   Therefore it is necessary to work hard to preserve the life of the patient in such critical condition in intensive care. After suffering critical conditions SSS, these patients require constant correction and support, since it is highly dependent on internal and external stimuli.
   In addition to internal variables vascular blood pipeline, it is also influenced by external factors - emotions meteofactors, physical activity. Among meteofactors- most important for adverse effects is atmospheric pressure, humidity levels, precipitation, wind speed, etc..). Therefore, these patients are meteosensitive early deregulation of the cardiovascular system.
   In the last 2 decades has found widespread acceptance anhiohirurhiya leading active tactics removing obstacles in the lumen of blood vessels, dramatically restores local permeability in a particular segment of the CCC, which led to clinical vascular accident.
   Today, however, is necessary to develop a new direction focused medical management of CAS under control monitoring tool based on the principles of evidence-based medicine with a deep knowledge of the functioning of the vascular blood pipeline - angiotherapy.
   Such approaches can increase the effectiveness of treatment on vascular pathology in 3-8 times depending on neglect mechanisms of chaos in the entire CAS.
   Mathematical modeling can simulate variations restructuring vasculature and to develop a theoretical model of optimal treatment plan combining anhiohirurhichnyh and angiotherapy effects that will achieve optimal results, reduce or even prophylaxis appearance reperfusion syndrome after angiotherapy interventions.